Multidrug-Resistant Acinetobacter baumannii

Multidrug-Resistant Acinetobacter baumannii

Resistance to multiple drugs has experienced alarming 60% increase in 10 years

Background

Drug-resistant Acinetobacter baumannii is a Gram-negative bacteria found primarily in hospital settings, where it frequently dwells on IV and catheter lines of ICU patients. Because of Acinetobacter’s low virulence, few colonized patients develop a disease. However, when an infection does occur, it often results in hospital-wide outbreaks and relatively high rates of mortality. In the outpatient setting, the pathogen has been associated with wound infections among soldiers, earning it the name “Iraqibacter.”

Acinetobacter spp are showing high intrinsic resistance to an increasing number of antibiotic classes, posing a global public health challenge. With the partial exception of tigecycline, fewnew drugs have been developed for this pathogen. Policies promoting new drug development and the large-scale vaccination of populations urgently need to be evaluated.