Healthcare-associated infections (HAIs) refer to infections acquired via health care settings, such as hospitals and nursing homes. HAIs can be life-threatening, but one-third or more of these infections are preventable. Infections may be acquired as a result of poor infection control, typically via medical devices or as a result of surgical procedures. HAIs are more likely to be caused by antibiotic-resistant pathogens than are community-associated infections, because of the high intensity of antibiotic use and the prevalence of seriously ill patients in health care settings.

Reducing Rates of Healthcare-Associated Infections

The Center’s work on HAIs has focused on assessing the burden of these infections, incentives to reduce rates of HAIs, and institutional characteristics that may predict HAI prevention performance. CDDEP researchers estimated that, in 2006, nearly 50,000 deaths in the United States were attributable to two common types of HAIs, finding that much of the burden occurred among surgical patients.

Using a game-theory model of epidemiology and hospital behavior, CDDEP researchers assessed the impact of three different forms of subsidies: a subsidy tied to the number of uninfected patients, which is equivalent to a tax on infected patients; a fixed subsidy; and a dollar-for-dollar matching subsidy. The researchers found that a dollar-for-dollar matching subsidy, in which policymakers match hospital spending for infection control measures, was the most effective at reducing the number of hospital-acquired infections. In hospitals with high transmission and/or high levels of patients with infections on admission, a matching subsidy resulted in a hospital increasing its own spending. Additionally, in a two-hospital model, researchers demonstrated that subsidies should be preferentially given to hospitals with lower transmission rates in order to improve infection control for both facilities.